Strain-dependent effects on neurobehavioral and seizure phenotypes in Scn2a-K1422E mice

Strain-dependent effects on neurobehavioral and seizure phenotypes in Scn2a K1422E mice
All data reported in the above entitled manuscript are contained in this  workbook.
Contents:

Sheet 1: Zero Maze

Raw data for all subjects evaluated using the zero maze assay
Subjects are identified by study number in column A
Sex information (M, F) is given in column B
Strain information (B6, F1D2) is given in column C
Genotype information (WT, E/+) is given in column D
Time spent in open arms (% of total trial time, 5 minutes) is given in column E 
Total distance traveled (cm) is given in column F
***rows in red indicate subjects that exited the maze and were excluded***
Sheet 2: Open Field

Raw data for all subjects evaluated using the open field assay
Subjects are identified by study number in column A
Sex information (M, F) is given in column B
Strain information (B6, F1D2) is given in column C
Genotype information (WT, E/+) is given in column D
Time spent in center zone (% of total trial time, 10 minutes) is given in column E 
Total distance traveled (cm) is given in column F
Sheet 3: Kainic Acid Seizure Induction: Binned

Raw data reflecting highest seizure stage reached within 5 minute bins for all subjects following kainic acid administration
Subjects are identified by study number in column A
Sex information (M, F) is given in column B
Strain information (B6, F1D2) is given in column C
Genotype information (WT, E/+) is given in column D
Highest seizure stage (1-7) reached per 5 min time bin is given in columns E-AB
***For columns E-AB, after a subject reaches stage 7 (death) all subsequent bins are scored as 7***
Legend for modified Racine scale stages is given in columns AD-AE
Sheet 4: Kainic Acid Seizure Induction: Latency

Raw data reflecting latency to first occurrence of each seizure stage for all subjects following kainic acid administration
Subjects are identified by study number in column A
Sex information (M, F) is given in column B
Strain information (B6, F1D2) is given in column C
Genotype information (WT, E/+) is given in column D
Latency (min) to each seizure stage is given in columns E-K
***For columns E-K, a dash (-) indicates a subject did not reach that seizure stage in the 120 min trial period*** 
Legend for modified Racine scale stages is given in columns M-N
***rows in red indicate subjects that died shortly after the 120 min trial period***