A novel ERK substrate regulates wide varieries of IEGs
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https://www.ncbi.nlm.nih.gov/sra/SRP307517
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资源简介：
The ERK pathway induces cell proliferation in response to growth factor stimulation. Although ERK controls various transcription factors in the nucleus, gene regulation mechanisms underlying the rapid IEG inductions were not fully elucidated. Here we report that ERK phosphorylates an unique novel substrate. We found that ERK facilitates rapid transcription of IEGs through the phosphorylation of the substrate. Overall design: mRNA expressions of EGF-treated or non-treated HEK293-WT and -4A cells
创建时间：
2023-01-05
