Pharmacotherapeutic strategies for the management of erectile dysfunction in patients with diabetes and pre-diabetes

Erectile dysfunction (ED) is a neglected complication in patients with pre-diabetes or diabetes mellitus (DM). A summary and review of the role of standard ED treatment and the contribution of lifestyle modification and hypoglycemic drugs. Oral phosphodiesterase type 5 inhibitors (PDE5i) represent the first-line therapy even in patients with DM. Testosterone replacement therapy (TRT) is mandatory in all hypogonadal (total testosterone