IL-1Ã promotes the proliferation of rat chondrocytes and inhibits the proliferation of mouse chondrocytes. Overall design: To choose a suitable in-vitro cell model for studying OA, RNA samples from r
Values are pg/mL, shown as mean ± SEM (n = 3 samples per group, pooled pairs from 6 animals). Significant differences compared to naïve animals are shown as *(p<0.05), **(p<0.01) and ***(p<0.001); com
Leukotrienes have been implicated in the regulation of immune responses, including inflammation and immediate hypersensitivity reactions. Here, we describe the phenotypic analysis of leukotriene-defic
We report that a novel synthetic BET inhibitor, JQ1, exerts potent anti-inflammatory effects on LPS-stimulated bone marrow derived macrophages (BMDMs) which were isolated from C57BL6 mice.
