PRMT5:MEP50 complexed with inhibitor PF-06855800
收藏Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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https://pdbj.org/mine/summary/7mxa
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资源简介：
PRMT5:MEP50 complexed with inhibitor PF-06855800 Descriptor: 7-[(5R)-5-C-(4-chloro-3-fluorophenyl)-beta-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Methylosome protein 50, Protein arginine N-methyltransferase 5 Authors: McTigue, M, Deng, Y.L, Liu, W, Brooun, A. Deposit date: 2021-05-18 Release date: 2021-11-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.713 Å) Cite: SAM-Competitive PRMT5 Inhibitor PF-06939999 Demonstrates Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance. Mol.Cancer Ther., 21, 2022
创建时间：
2021-05-18
