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Genes commonly and differentially regulated by MYCN and WDR5 in IMR32 cells.

NIAID Data Ecosystem2026-05-01 收录

数据链接：

https://figshare.com/articles/dataset/Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_/25504189 数据链接链接失效反馈

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Genes commonly and differentially regulated by MYCN and WDR5 in IMR32 cells.

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创建时间：

2024-03-28

神经母细胞瘤转录调控

MYCN增强子结合

In neuroblastoma, amplification of the oncogenic basic helix-loop-helix (bHLH) transcription factor (TF) MYCN is the defining prognosticator of high-risk disease, occurs in one-third of neuroblastoma,

NIAID Data Ecosystem90

Genome-wide chromatin-immunoprecipitation studies for ISL1 in SH-SY5Y neuroblastoma cell line. Homo sapiens

神经母细胞瘤转录调控

功能基因组学

The LIM-homeodomain transcription factor ISL1 plays an essential role in sympathetic neuronogenesis. Expression of ISL1 has been associated with neuroblastoma, a pediatric tumor derived from sympatho-

NIAID Data Ecosystem50

LIN28B Regulates Transcription and Potentiates MYCN-induced Neuroblastoma in a let-7-independent Manner [ChIP-seq]

神经母细胞瘤转录调控

ChIP-seq表观遗传学

LIN28B is highly expressed in neuroblastoma and promotes tumorigenesis at least in part through inhibition of let-7 microRNA biogenesis. Here, we report that overexpression of either wild-type LIN28B,

NIAID Data Ecosystem20

GSM8112043_KPNYN_GATA3_4_R1.bigWigNeuroblastoma cell lines

表观遗传学

神经母细胞瘤转录调控

Cut and Run signal tracks from Neuroblastoma cell lines

Figshare2024-05-16 更新80

TCF4 is a key mediator of cell identity in neuroblastoma and vulnerable to protein degradation by multiple epigenetic factors [RNA-seq]

神经母细胞瘤转录调控

疾病靶点发现

Neuroblastomas (NBs) are aggressive pediatric tumors that are responsible for up to 15% of all pediatric cancer deaths. Two differentiation states exist in NB tumors, a majority of more committed ADRN

NIAID Data Ecosystem20

Genes commonly and differentially regulated by MYCN and WDR5 in IMR32 cells.

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