Demographics, hemodynamics, Pulmonary Function Testing and Cardiopulmonary Exercise Testing parameters in IPAH patients and Control subjects.

Values are expressed as mean ± SD and percentage of measured to predicted values (%pred).
*p<0.05, †p<0.005, ‡p<0.0001, vs. controls using unpaired t test. NA = not applicable.
NYHA  =  New York Heart Association functional classification; mPAP  =  mean pulmonary artery pressure; mRAP = mean right atrial pressure; mPWP = mean pulmonary artery wedge pressure; TPVR  =  total pulmonary vascular resistance; FVC  =  forced vital capacity; FEV1  =  forced expiratory volume in 1 second; MVV  =  maximum voluntary ventilation; DLCO  =  gas transfer index or diffusing capacity for carbon monoxide; TLC  =  total lung capacity; AT  =  anaerobic threshold; %MVV  =  percentage of maximum voluntary ventilation; PETCO2  =  partial pressure of end-tidal carbon dioxide; OUES  =  oxygen uptake efficiency slope; OUEP  =  oxygen uptake efficiency plateau; IPAH  =  idiopathic pulmonary arterial hypertension; %pred  =  percent of predicted; V˙O2  =  peak oxygen uptake, STPD  =  standard temperature pressure dry; V˙E  =  minute ventilation, BTPS  =  body temperature pressure saturated; V˙CO2  =  carbon dioxide output, STPD.