Demographics, hemodynamics, Pulmonary Function Testing and Cardiopulmonary Exercise Testing parameters in IPAH patients and Control subjects.

Values are expressed as mean ± SD and percentage of measured to predicted values (%pred). *p<0.05, †p<0.005, ‡p<0.0001, vs. controls using unpaired t test. NA = not applicable. NYHA = New York Heart Association functional classification; mPAP = mean pulmonary artery pressure; mRAP = mean right atrial pressure; mPWP = mean pulmonary artery wedge pressure; TPVR = total pulmonary vascular resistance; FVC = forced vital capacity; FEV1 = forced expiratory volume in 1 second; MVV = maximum voluntary ventilation; DLCO = gas transfer index or diffusing capacity for carbon monoxide; TLC = total lung capacity; AT = anaerobic threshold; %MVV = percentage of maximum voluntary ventilation; PETCO2 = partial pressure of end-tidal carbon dioxide; OUES = oxygen uptake efficiency slope; OUEP = oxygen uptake efficiency plateau; IPAH = idiopathic pulmonary arterial hypertension; %pred = percent of predicted; V˙O2 = peak oxygen uptake, STPD = standard temperature pressure dry; V˙E = minute ventilation, BTPS = body temperature pressure saturated; V˙CO2 = carbon dioxide output, STPD.