BIRC6-targeting as potential therapy for advanced, enzalutamide-resistant prostate cancer
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资源简介：
New transplantable patient-derived xenograft (PDX) CRPC model with intrinsic ENZ-Resistance were used to access therapeutic efficacy of BIRC6 targeting antisense oligonucleotide (ASO-6w2). Molecular pathways associated with the inhibitory effect of ASO-6w2 vs control Scrb ASO were examined by gene expression profiling. Patient-derived xenograft tumors from the LTL313BR xenograft lineage (PMID: 24356420) after treatment with BIRC6 targeting ASO or control ASO for 3 weeks (5 day on, 2 day off)
创建时间：
2016-10-11
