Host microbiota constantly control maturation and function of microglia in the central nervous system (part 2)

ChEBI2015-05-25 更新2026-07-12 收录

微生物-肠-脑轴

胶质细胞功能

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-67857 数据链接链接失效反馈

官方服务：

资源简介：

Host microbiota constantly control maturation and function of microglia in the central nervous system (part 2)

创建时间：

2015-05-25

Astrocytic PERK deficiency drives prefrontal circuit dysfunction and depressive-like behaviors

抑郁症神经机制

胶质细胞功能

Major depressive disorder (MDD) is associated with dysfunction in prefrontal cortex (PFC) circuits, yet the glial mechanisms underlying these abnormalities remain unclear. Here, downregulation of the

NIAID Data Ecosystem60

Oligodendrocyte Precursor Cells Synthesize Neuromodulatory Factors

胶质细胞功能

神经调节因子表达

NG2 protein-expressing oligodendrocyte progenitor cells (OPC) are a persisting and major glial cell population in the adult mammalian brain. Direct synaptic innervation of OPC by neurons throughout th

Figshare2016-01-15 更新10

Single nuclei RNAseq datasets supporting the impact of primary cilia deficiency on astrocytes’ intercellular connectivity and neuronal transcriptomes in the brain.. Single nuclei RNAseq datasets supporting the impact of primary cilia deficiency on astrocytes’ intercellular connectivity and neuronal transcriptomes in the brain.

胶质细胞功能

神经细胞转录组学

Astrocyte diversity is greatly influenced by local environmental modulation. In this study, we analyzed the impact of ciliary deficient astrocytes on astrocytes’ intercellular communications and neuro

NIAID Data Ecosystem00

Single cell deletion of the transcription factors Sox9 and Trps1 reveals novel functions in adult cortical astrocytes [Spatial transcriptomics]

胶质细胞功能

空间转录组学

Astrocytes play key roles in brain function but it is still poorly understood how these are orchestrated by pan-astrocyte transcriptions factors (TFs). Here we examined the function of the well-known

NIAID Data Ecosystem10

Data From: PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation

帕金森病发病机制

胶质细胞功能

Source data files for Wang et al 'PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation'

Zenodo2025-04-25 更新10