microRNA-seq of Kynurenine stimulated mouse spleenocyte in vitro

RNA-seq technology was confirmed that miRNA expression has an important role in vaccine adjuvant in vivo and in vitro. Kynurenin, as an immunosuppressive adjuvant, but the exact mechanism of action with immune cells is still poorly understood. In the present study, RNA and miRNA sequencing was performed in mouse splenocytes stimulated by Kynurenin. These data provide an important basis for understanding the mechanisms underlying Kyn as an immunosuppressive adjuvant regulated the immune response. Four control samples and four Kynurenin(40μg/ml) treated samples