Impact of KIF26A loss in human forebrain organoids
收藏NIAID Data Ecosystem2026-03-14 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP397101
下载链接
链接失效反馈官方服务：
资源简介：
KIF26A is an unconventional kinesin that lacks motor activity. To characterize its role in brain development, we generated KIF26A knock-out iPSC lines and differentiated forebrain organoids. We performed single cell RNA sequencing at Day 60 and Day 80 to compare between control and KIF26A-deleted organoids at the molecular level, which revealed cell type-specific transcriptional changes in MAPK, MYC and E2F pathways. Overall design: Control and KIF26A-deleted organoids were collected at Day 60 and 80, dissociated into single cells and captured using 10X Chromium platform.
创建时间：
2022-12-21
