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Inhibition of Lymphotoxin-LIGHT Signaling Reduces the Interferon Signature in Rheumatoid Arthritis Patients

ChEBI2015-05-14 更新2026-07-21 收录

关节炎病理机制

LIGHT信号通路抑制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-45291 数据链接链接失效反馈

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Inhibition of Lymphotoxin-LIGHT Signaling Reduces the Interferon Signature in Rheumatoid Arthritis Patients

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创建时间：

2015-05-14

关节炎病理机制

细胞外基质-细胞相互作用

Rheumatoid arthritis (RA) is an inflammatory autoimmune disease affecting synovial joints and leading to cartilage damage and bone loss. This destruction is promoted by activated fibroblast-like synov

NIAID Data Ecosystem80

DataSheet1_Melatonin Maintains Anabolic-Catabolic Equilibrium and Regulates Circadian Rhythm During Osteoarthritis Development in Animal Models: A Systematic Review and Meta-analysis.doc

关节炎病理机制

褪黑素昼夜节律调节

Background: The driving force behind osteoarthritis (OA) pathogenesis is an anabolic-catabolic (a/c) imbalance. Melatonin (MT) is a key player in maintaining a/c stability and mitigates OA pathogenesi

NIAID Data Ecosystem50

Implication of bone marrow adipose tissue in bone homeostasis during osteoarthritis

关节炎病理机制

骨髓脂肪细胞功能

Objective: To explore the role of bone marrow adipocytes (BMAds) in osteoarthritis (OA). Methods: Male and female C57BL/6 mice (n=4/group) underwent meniscectomy (MNX) or SHAM surgery. OA was determin

NIAID Data Ecosystem40

Gene expression alteration in mouse primary chondrocytes by cyclic tensile strain.

软骨细胞生物力学响应

关节炎病理机制

To investigate effects of excessive mechanical loading on chondrocytes. Primary chondrocytes were isolated from 6-day-old C57BL/6J mice, and were subjected to cyclic tensile strain (0.5 Hz, 10% elonga

NIAID Data Ecosystem60

Additional file 1: of Pigment Epithelium-Derived Factor (PEDF) mediates cartilage matrix loss in an age-dependent manner under inflammatory conditions

软骨退行性病变

关节炎病理机制

Datasets. Datasets used for quantification. In figures where data are quantified, the datasets are included in tabs of this Excel file labeled by figure number or data described. The “Fig. 2” tab incl

Figshare2017-01-26 更新40

Inhibition of Lymphotoxin-LIGHT Signaling Reduces the Interferon Signature in Rheumatoid Arthritis Patients

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