Crystal structure of the first bromodomain of human BRD4 in complex with MA4-022-2
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Crystal structure of the first bromodomain of human BRD4 in complex with MA4-022-2 Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ~{N}-[2-chloranyl-5-[[2-[[3-fluoranyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-5-methyl-pyrimidin-4-yl]amino]phenyl]-2-methyl-propane-2-sulfonamide Authors: Ember, S.W, Zhu, J.-Y, Schonbrunn, E. Deposit date: 2015-12-04 Release date: 2017-02-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Potent Dual BET Bromodomain-Kinase Inhibitors as Value-Added Multitargeted Chemical Probes and Cancer Therapeutics. Mol. Cancer Ther., 16, 2017
创建时间:
2015-12-04



