Genome resequencing data of adaptive laboratory evolved E. coli W
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https://www.ncbi.nlm.nih.gov/sra/SRP295643
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Using a synthetic biosensor to couple production of a specific metabolite with cell growth, we spontaneously evolved cells under the selective condition toward the acquisition of genotypes that optimally reallocated cellular resources. Using 3-hydroxypropionic acid (3-HP) production from glycerol in Escherichia coli as a model system, we found spontaneous mutations in the conserved regions of AC and CRP. Overall design: Comparison of genomic DNA between parental and evolved E. coli W strain
创建时间:
2021-11-23



