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IL-17 Signaling in Steatotic Hepatocytes and Macrophages Promotes Alcoholic Liver Disease-induced Hepatocellular Carcinoma

NIAID Data Ecosystem2026-03-14 收录

酒精性肝病肝癌机制

IL-17信号通路

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE139841 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2022-10-31

肾移植排斥

IL-17信号通路

Genesets for the IL-17 pathway and Th17 T-helper cell subtype showed increasing enrichment in 33 pre-transplant donor biopsies and 33 matching post-transplant biopsies from patients with increasing Ba

NIAID Data Ecosystem70

Crystal Structure of IL-17A/Fab6785 complex

抗体-抗原复合物

IL-17信号通路

Crystal Structure of IL-17A/Fab6785 complex Descriptor: CHLORIDE ION, Fab6785 heavy chain, Fab6785 light chain, ... Authors: Luo, J, Gilliland, G.L, Malia, T, Obmolova, G, Teplyakov, A. Deposit date:

Protein Data Bank Japan2024-10-16 更新70

The spectrum of mild-to-severe psoriasis vulgaris is defined by a common activation of IL-17 pathway genes, but with key differences in immune regulatory genes. Homo sapiens

银屑病基因表达谱

IL-17信号通路

Mild vs. severe psoriasis vulgaris is often distinguished by the Psoriasis Area and Severity Index. It is widely assumed that severe psoriasis involves higher levels of skin inflammation, but comparat

NIAID Data Ecosystem40

Inhibition of Bromodomain and Extra Terminal (BET) domain activity modulates the IL-23R/IL17 axis and suppresses acute Graft-Versus-Host Disease. Inhibition of Bromodomain and Extra Terminal (BET) domain activity modulates the IL-23R/IL17 axis and suppresses acute Graft-Versus-Host Disease

移植物抗宿主病

IL-17信号通路

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem70

Human blood monocyte response to IL-17A in culture. Homo sapiens

单细胞免疫应答

IL-17信号通路

The levels of IL-17 are elevated in the serum of psoriasis patients. However, the effects of IL-17 on circulating leukocytes bearing the IL-17 receptors are not fully understood. Of particular interes

NIAID Data Ecosystem50

IL-17 Signaling in Steatotic Hepatocytes and Macrophages Promotes Alcoholic Liver Disease-induced Hepatocellular Carcinoma

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