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N6-methyladenosine mRNA Modification Is Essential for Human Pancreatic Lineage Specification

NIAID Data Ecosystem2026-03-13 收录

表观转录组学

胰腺细胞分化

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE163964 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2022-07-24

表观转录组学

染色质调控

The N6-methyladenosine (m6A) has been shown to regulate stability and translation of messenger RNA (mRNA) in various biological processes. Here, we show that the knockout of the m6A writer Mettl3 or a

NIAID Data Ecosystem80

Hakai is required for stabilizing core components of the m6A mRNA methylation machinery

m6ARNA修饰机制

表观转录组学

N6-methyladenosine RNA (m6A) is the most abundant internal modification on mRNA which influences most steps of mRNA metabolism and is involved in several biological functions, including circadian cloc

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The role of m6A/m-RNA methylation in stress response regulation

表观转录组学

神经病理机制

N6-Methyladenosine (m6A) and N6,2'-O-dimethyladenosine (m6Am) are abundant mRNA modifications that regulate transcript processing and translation. The role of both, here termed m6A/m, in the stress re

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Additional file 8 of ISL1 controls pancreatic alpha cell fate and beta cell maturation

胰腺细胞分化

表观遗传调控

Additional file 8: Dataset S3. ISL1 and H3K27me3 CUT&Tag-seq data analyses: pancreatic endocrine cells at P9.

Figshare2024-08-13 更新70

Additional file 10 of Changes in m6A RNA methylation are associated with male sterility in wolfberry

植物雄性不育机制

表观转录组学

Additional file 10: Table S9. GO enrichment results of hypomethylated genes.

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