4‑Aminosalicylic Acid Adducts
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https://figshare.com/articles/dataset/4_Aminosalicylic_Acid_Adducts/2428462
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资源简介：
4-Aminosalicylic
acid (p-aminosalicylic acid, PAS), an antituberculosis
drug, is a model active pharmaceutical ingredient to study salt and
cocrystal formation in a multiple hydrogen-bonding functionality molecule
with carboxylic acid, amine, and phenol groups. A cytosine salt CYT+–PAS–, salt cocrystal hydrate CYT+–PAS––CYT–H2O, and nicotinamide cocrystal hydrate PAS–NAM–H2O, are described in this article. Furthermore, X-ray crystal
structures of PAS sodium dihydrate, sulfate, and mesylate salts and
dehydration/rehydration behavior of the sodium salt by powder X-ray
diffraction are discussed.
创建时间：
2016-02-19
