Effect of fasting-refeeding on gene expression in young and old killifsh adipose tissue.

Fasting-refeeding paradigms result in drastic shifts in metabolism and gene expression patterns. The effect of fasting-refeeding changes between young and old individuals. We sought to decipher the changes in response to fasting-refeeding in young and old animals by profiling gene expression in adipose tissue of killifish Nothobranchius furzeri. Wild-type killifish N. furzeri GRZ-AD were fasted for 3 days and refed for 1 day at either young or old age. Young killifish were 7 weeks old compared to 18 weeks for the older time point.