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Protein Arginine Methyltransferase 6 dependent gene expression and splicing: Association with breast cancer outcomes

ChEBI2012-08-01 更新2026-07-21 收录

肿瘤分子标记物

RNA剪接调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-36542 数据链接链接失效反馈

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资源简介：

Protein Arginine Methyltransferase 6 dependent gene expression and splicing: Association with breast cancer outcomes

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创建时间：

2012-08-01

剪接保真度

RNA剪接调控

Fidelity of 3´-splice site (3´SS) selection by the spliceosome is critical for proper gene expression but is a daunting task considering the low complexity of the 3´SS consensus YAG. Here we show that

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Glucose dissociates DDX21 dimers to regulate mRNA processing and promote epidermal differentiation (RNA-Seq II)

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表皮细胞分化

Glucose is an important cellular energy source, however, glucose's function as a second messenger remains relatively unexplored. Here, we find that glucose binds directly to DDX21 to regulate its func

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Structure and Novel Functional Mechanism of Drosophila SNF in Sex-Lethal Splicing

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果蝇性别决定

Sans-fille (SNF) is the Drosophila homologue of mammalian general splicing factors U1A and U2B″, and it is essential in Drosophila sex determination. We found that, besides its ability to bind U1 snRN

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ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing. ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing

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神经元mRNA处理

ELAV/Hu factors are conserved RNA binding proteins that play diverse roles in mRNA processing and regulation. The founding member, Drosophila Elav, was recognized as a vital neural factor 35 years ago

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The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation

RNA剪接调控

翻译控制

Recent work has associated point mutations in both zinc fingers (ZnF) of the spliceosome component U2AF35 with malignant transformation. However, surprisingly little is known about the functionality o

NIAID Data Ecosystem30

Protein Arginine Methyltransferase 6 dependent gene expression and splicing: Association with breast cancer outcomes

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