Summary of GWAS and follow-up genotyping results for association with SCD.

Chr, chromosome; AF, allele frequency of coded allele (weighted by study size); OR, odds ratio; CI, confidence interval. Follow-up genotyping results are reported for 1,730 SCD cases and 10,530 controls, with the exception of rs12601622 (1,460 SCD cases, 10.182 controls), which failed genotyping in the Oregon-SUDS follow-up study. Bold indicates nominal significance (P<0.05) for validation. P-values for validation are reported as one-sided, and NA indicates opposite direction of effect from GWAS. *Includes ARREST (719 SCD cases, 4,190 controls) and AGNES (670 SCD cases, 654 controls) studies.