Institut Pasteur BAG - Structural biology of infectious agents

The Institut Pasteur’s BAG gathers the projects of the research units and platforms of the Institut Pasteur in Paris which are active in the field of structural biology: Structural Microbiology (P.M. Alzari), Structural Dynamics of Macromolecules (M. Delarue), Structural Virology (F. Rey) and the Platform of Crystallography (A. Haouz). A non-exhaustive list of ongoing projects includes: - actinobacterial cell division proteins, central metabolic enzymes and their complexes; - DNA gyrases, topoisomerases and regulators from mycobacteria or model organisms; - eukaryotic and archeal DNA polymerases and replisome proteins; - viral envelope proteins from pathogenic viruses, and their complexes with neutralizing antibodies; - enzymes and structural proteins from other human pathogens, supported by evolving national and international collaborations.