Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-279 N-[(4-chlorophenyl)methyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-279 N-[(4-chlorophenyl)methyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine Descriptor: DIMETHYL SULFOXIDE, N-[(4-chlorophenyl)methyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Polymerase acidic protein Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2016-02-25 Release date: 2017-02-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA To Be Published