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Crystal structure of MYST acetyltransferase domain in complex with inhibitor 39

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Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Crystal structure of MYST acetyltransferase domain in complex with inhibitor 39 Descriptor: 5-ethoxy-2-fluoro-3-methyl-N'-(phenylsulfonyl)benzohydrazide, GLYCEROL, Histone acetyltransferase KAT8, ... Authors: Hermans, S.J, Parker, M.W, Thomas, T, Baell, J.B. Deposit date: 2019-06-18 Release date: 2020-04-01 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.738 Å) Cite: Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents. J.Med.Chem., 63, 2020

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2019-06-18
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