Vulliard2021_BioProfilingJl

# High-content imaging chemical screen in U-2-OS<br><br>This dataset is described in the manuscript untitled "BioProfiling.jl: Profiling biological perturbations with high-content imaging in single cells and heterogeneous populations" by Vulliard _et al_ (DOI: [10.1101/2021.06.18.448961](https://doi.org/10.1101/2021.06.18.448961).<br>The following files are made available:<br><br>* `README.md`: description of the dataset.<br>* `750CellsPerWell.zip`: raw fluorescent images (TIFF) for a 384-well drug plate seeded with 750 cells per well.<br>* `1500CellsPerWell.zip`: raw fluorescent images (TIFF) for a 384-well drug plate seeded with 1500 cells per well.<br>* `Batch_data_u2os_drug.cpproj`: CellProfiler 3.1.8 pipeline used to analyse the images.<br>* `data.zip`: morphological measurements from CellProfiler per cell for each plate and plate layout. Necessary input to reproduce our [example analyses](https://github.com/menchelab/BioProfilingNotebooks).* `IntermediateResults.zip`: files generated in the [example analyses](https://github.com/menchelab/BioProfilingNotebooks).that are not required but helpful to avoid rerunning all scripts in order.<br><br>The preparation of the drug plates is described more precisely in the manuscript.