Modulation of glutamine metabolism by the PI3K-PKB/c-akt-FOXO network regulates autophagy

NIAID Data Ecosystem2026-03-07 收录

自噬调控

Akt-FOXO信号通路

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA152043 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

创建时间：

2012-07-22

cAMP-Protein kinase A and stress-activated MAP kinase signaling mediate transcriptional control of autophagy in fission yeast during glucose limitation or starvation

自噬调控

酵母生物学

Macroautophagy/autophagy is an essential adaptive physiological response in eukaryotes induced during nutrient starvation, including glucose, the primary immediate carbon and energy source for most ce

DataCite Commons2025-02-10 更新90

Data from: HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels

自噬调控

磷脂酸转运

A fundamental question is how autophagosome formation is regulated. Here we show that the PX domain protein HS1BP3 is a negative regulator of autophagosome formation. HS1BP3 depletion increased the fo

DataONE2016-12-27 更新80

Hypoxia-induced autophagy drives colorectal cancer initiation and progression by activating the PRKC/PKC-EZR (ezrin) pathway

肿瘤生物学

自噬调控

In solid tumors, cancer stem cells (CSCs) or tumor-initiating cells (TICs) are often found in hypoxic niches. Nevertheless, the influence of hypoxia on TICs is poorly understood. Using previously esta

DataCite Commons2021-05-08 更新70

Silica nanoparticles induce autophagosome accumulation via activation of the EIF2AK3 and ATF6 UPR pathways in hepatocytes

纳米颗粒毒性

自噬调控

Autophagy dysfunction is a potential toxic effect of nanoparticles. Previous studies have indicated that silica nanoparticles (SiNPs) induce macroautophagy/autophagy dysfunction, while the precise mec

DataCite Commons2024-02-20 更新90

Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis [RNA-seq]

牙齿发育

自噬调控

The goal of this study is to compare transcriptome profiling (RNA-seq) of proximal end of incisor 1 week after TMX induction between control and Fgfr1 mutant mice mRNA profiles of control and Fgfr1 mu

NIAID Data Ecosystem80

Modulation of glutamine metabolism by the PI3K-PKB/c-akt-FOXO network regulates autophagy

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