A systems approach identifies progeroid Ercc1[-/Δ] mice as a model system for kidney aging.
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE43061
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Using these samples, it has been shown that the transcriptional landscape in glomeruli of Ercc1[-/Δ] mice at a rather young age of 14 weeks mimics that of mice which have undergone real-life renal aging. Thus, young Ercc1[-/Δ] mice can be used as a model system for glomerular aging in future studies. The RNAs origin from glomerular tissues of mice of 2 distinct genotypes at 3 distinct stages of age. Between 3 and 6 replicates have been prepared per group.
创建时间：
2019-03-04
