Healthy participants from Jamaica: Test for association of F cell levels with HMIP-2 markers.
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The multiple-regression model included covariates age, sex, and an additive genetic effect of the XmnI G�� site. The minor-allele frequency (MAF) refers to the same allele in all populations.Genetic association was also tested in the combined Jamaican group (Afro-Caribbean and Afro-German groups combined). The last column is a repeat of this analysis, after exclusion of individuals who carry the C allele of rs9376090 (I-01, 7 homozygotes and 95 heterozygotes), which tags non-African haplotypes at the HMIP-2 locus. Also excluded were 16 individuals with an unknown genotype at this SNP. Hence, a total of 693 individuals were analysed in the combined Jamaican group.*A nominally significant (P = 0.04) dominance effect was detected only for I-11 in the AG group and was included in the regression model for this data point.?rs35959442 was previously named rs52090909.
创建时间:
2015-12-02



