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ChIP-seq of in vitro differentiated naïve and Th9 cells

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NIAID Data Ecosystem2026-05-01 收录
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To investigate changes in chromatin accessibility over time, we differentiated Th9 cells in vitro from naïve T cells from human and murine sources, and followed them over an extended time course, during which they gained and then lost capacity for IL-9 production We then performed Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for histone modifications H3K4me1, K3K4me3, and H3K27Ac in cells from 2 different human donors and from 2 mice at 4 time points. Overall design: Peaks for various histone marks normalized to input

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2023-04-29
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