RNA-mediated double-strand break repair by end-joining mechanisms
收藏NIAID Data Ecosystem2026-03-14 收录
下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA883674
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资源简介：
Uncover a direct role of RNA in DNA double-strand break (DSB) repair in human cells. Plasmid systems having different RNA sequences or different levels of transcription were used to do a transient genetic assay in human cells. DSBs were induced on the plasmid constructs by CRISPR-Cas9 system, and the result of DSB repair was detected by Next-Generation Sequencing (NGS). Our customized NGS library preparation method enables to deeply sequence the DSB locus.
创建时间：
2022-09-23
