Comparative genomics reveals Chd1 as a determinant of nucleosome spacing in vivo

Alliance of Genome Resources2026-08-01 收录

核小体间距调控

Chd1功能

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https://www.yeastgenome.org/dataset/GSE66979 数据链接链接失效反馈

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We generated S.cerevisiae strains in which endogenous copies of candidate nucleosome spacing factors were replaced with the K.lactis copies

Comparative genomics reveals Chd1 as a determinant of nucleosome spacing in vivo. Saccharomyces cerevisiae

核小体间距调控

染色质重塑因子功能

We generated S.cerevisiae strains in which endogenous copies of candidate nucleosome spacing factors were replaced with the K.lactis copies. With this candidate approach, we found that K.lactis Chd1 d

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Human SMARCA5 Is Continuously Required to Maintain Nucleosome Spacing

核小体间距调控

SMARCA5功能研究

Western blot image from Figure 1B. The top half is an immunoblot with anti-SMARCA5 and the bottom half is an immunoblot with anti-GAPDH. On a PDVF membrane. Grayscale image of IR700 channel via LICOR

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Purified FLAG-Hrp1 GeLC-MS/MS - CHD1 remodelers regulate nucleosome spacing in vitro and align nucleosomal arrays over gene coding regions in S

染色质重塑

核小体间距调控

Proteomics on affinity purified and mock purified FLAG-Hrp1. Reduction with DTT, alkylation by iodoacetamide. 1D gel, tryptic in gel digestion of cut-out bands, GeLC-MS/MS.

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The ISW1 and CHD1 ATP-dependent chromatin remodelers compete to set nucleosome spacing in vivo

核小体间距调控

染色质重塑酶

We addressed the roles of three nucleosome spacing enzymes (ISW1, ISW2 and CHD1) in specifying chromatin organization in S. cerevisiae. Overall design: Comparison of budding yeast nucleosome positions

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Comparative genomics reveals Chd1 as a determinant of nucleosome spacing in vivo

核小体间距调控

染色质结构

NIAID Data Ecosystem30