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Fully defined NGN2 neuron protocol reveals diverse signatures of neuronal maturation

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE266359
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This bulk RNAseq dataset is part of a dataset described in the manuscript titled "Fully defined NGN2 neuron protocol reveals diverse signatures of neuronal maturation". This dataset includes NPC derived neurons using a wild type iPSC line, and was used to validate a MS-117 maturation score which attempt to establish a socre system to assess neuronal maturation with iPSCs derived neurons. Three technical replicates were included, and cells were profiled at the NPC stage, as well as cultures undergo neuronal differentiation and maturation at 4 weeks, weeks and 12 weeks upon the induction of terminal differentiation.
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2024-09-13
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