Identification of novel MeCP2 cancer-associated target genes
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Identification of novel MeCP2 cancer-associated target genes
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2020-10-02
相关数据集
Molecular pathogenesis of several neurodevelopmental disorders converges on MeCP2-TCF20 complex interactions
Neurodevelopmental disorders (NDDs) are genetically heterogeneous, yet often share certain features such as intellectual disability or motor incoordination. MeCP2 dysfunction is associated with MECP2
NIAID Data Ecosystem60
Identification of the methyl-CpG binding protein 2 (MeCP2) interacting proteins in the high molecular weight (HMW) extract prepared from the human HEK293T cells by immunoprecipitation coupled with mass spectrometry analysis
Identification of the methyl-CpG binding protein 2 (MeCP2) interacting proteins in the high molecular weight (HMW) extract prepared from the human HEK293T cells by immunoprecipitation coupled with mas
integrated proteome resources50
MeCP2 represses the rate of transcriptional initiation of highly methylated long genes (ChIP-Seq II)
Mutations in the methyl-DNA-binding repressor protein MeCP2 cause the devastating neurodevelopmental disorder Rett syndrome. It has been challenging to understand how MeCP2 regulates transcription bec
NIAID Data Ecosystem30
Hypothalamic gene expression data from Mecp2-null and MECP2-transgenic mice
We compared gene expression changes in the hypothalamus of mice lacking MeCP2 (Mecp2-null) and mice overexpressing MeCP2 (MECP2-transgenic). Mutations in the gene encoding the transcriptional represso
NIAID Data Ecosystem60
MeCP2 regulates genome-wide gene expression through recognition of H3K27me3 [NanoString]
MeCP2 plays a multifaceted role in gene expression regulation and chromatin organization. Interaction between MeCP2 and methylated DNA to regulate gene expression is well established. However, the wid
NIAID Data Ecosystem40
