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Blockade of IL-1b and PD-1 with combination chemotherapy reduces systemic myeloid suppression in metastatic pancreatic cancer with heterogeneous effects in the tumor

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NIAID Data Ecosystem2026-05-02 收录
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Clinical and translational results from a phase Ib trial testing whether IL-1β blockade in human pancreatic cancer would alleviate myeloid immunosuppression and reveal anti-tumor T cell responses to PD-1 blockade. Single-cell RNA-seq analysis of pre- and post-treatment samples from the phase Ib trial

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2024-09-30
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