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Multi-omics profiling visualizes dynamics of cardiac development and functions [ChIP-Seq]

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE213572
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Cardiogenesis is a tightly-regulated dynamic process through a continuum of differentiation and proliferation events. Transcriptional activation is the predominant early step for initiating cardiac formation in mammals. We then applied ChIP-seq analysis against histone modifications H3K4me1, H3K4me3, H3K27ac and RNAPol II in E10.5 mouse hearts to evaluate the instant activity of transcription factors, which is believed to serve as a powerful tool to study regulatory processes. ChIP-seq for the histone modifications H3K4me1, H3K4me3, H3K27ac and RNA pol II of mice hearts from embryonic day 10.5.
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2023-01-15
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