Supporting data for "On the origin and evolution of RNA editing in metazoans"

Extensive adenosine-to-inosine (A-to-I) editing of nuclear-transcribed RNAs is the hallmark of metazoan transcriptional regulation, and is fundamental to numerous biochemical processes. Here we explore the origin and evolution of this regulatory innovation, by quantifying its prevalence in 22 species that represent all major transitions in metazoan evolution. <br> <strong>Files provided in this dataset:</strong> 1. <strong>Genebody_Anno.tar.gz </strong>: Refined gene annotations of the 22 species used in this study in gene transfer format (GTF). 2. <strong>Repeat_Anno.tar.gz</strong> : Refined repeat annotation of the 22 species used in this study in gene transfer format (GTF). 3. <strong>Go_Anno.tar.gz </strong>: Gene ontology annotations of coding genes of the 22 species used in this study. 4. <strong>BlastBesthit.tar.gz</strong> : Best hit of coding genes of the 22 species used in this study returned by Blast searching to the NCBI NR database. 5. <strong>ResTable.tar.gz</strong> : RNA editing sites set of the 22 species identified in this study. 6. <strong>HyperEditingManual.tar.gz </strong>: Important manual scripts and pipelines including hyper-editing sites identification used in this study.<strong> </strong>