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3‑Arylsulfonylquinolines from <i>N</i>‑Propargylamines via Cascaded Oxidative Sulfonylation Using DABSO

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NIAID Data Ecosystem2026-03-13 收录
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We report a cascaded oxidative sulfonylation of N-propargylamine via a three-component coupling reaction using DABCO·(SO2)2 (DABSO). 3-Arylsulfonylquinolines were obtained by mixing diazonium tetrafluoroborate, N-propargylamine, and DABSO under argon atmosphere in dichloroethane (DCE) for 1 h. In a radical pathway, DABSO was utilized as the sulfone source and an oxidant in this radical-mediated cascaded reaction.

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2022-05-05
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