Differentially expressed genes in H. pylori wild-type P12 modH5 ON versus the mutant strain P12ΔmodH5.

aThe genes listed are either down- or up- regulated in the H. pylori P12ΔmodH5 mutant strain. The identity of the gene is indicated with the gene ID in the annotation of the H. pylori P12 genome [42].bThe ratio presented is the mean of H. pylori P12ΔmodH5 mutant:wild-type P12modH5 ON from multiple replicate spots on three independent microarrays. Only those genes with an expression ratio ≥1.5-fold were included in this study.cDetermined using LIMMA [41].dGene expression confirmed by quantitative RT-PCR (QRT-PCR) in the wild-type H. pylori P12modH5 ON strain and the H. pylori P12modH5 OFF strain. Results for each gene were as follows: HPP12_253 (5.10± 0.375), HPP12_255 (3.50± 0.346), HPP12_609 (−3.81 ± 0.184), HPP12_904 (−3.52± 0.290).