Crystal structure of human FPPS in complex with an allosteric inhibitor MIT-01-102
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Crystal structure of human FPPS in complex with an allosteric inhibitor MIT-01-102 Descriptor: Farnesyl pyrophosphate synthase, GLYCEROL, PHOSPHATE ION, ... Authors: Park, J, Berghuis, A.M. Deposit date: 2018-11-28 Release date: 2019-11-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2 Å) Cite: Chirality-Driven Mode of Binding of alpha-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). J.Med.Chem., 62, 2019
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2018-11-28
