Collaborative Cohort of Cohorts for COVID-19 Research (C4R): REasons for Geographic and Racial Differences in Stroke (REGARDS)

Cohort DescriptionThe REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort is one of the nation's largest, most comprehensive population-based cohorts, and it uses innovative home- and telephone-based data collection. REGARDS centrally recruited and initially examined 30,239 Black and White men and women aged ≥45 years in 2003-7 to understand why Southerners and Black Americans have a higher incidence of stroke and related diseases that affect brain health.Data Being Submitted Wave 1 questionnaire data includes 397 variables for 8109 REGARDS participants in C4R. Wave 2 questionnaire data includes 448 variables for 6421 REGARDS participants in C4R. Dried Blood Spot/Serosurvey data includes 7 variables for 4058 REGARDS participants in C4R. Derived data includes 43 variables for 8606 REGARDS participants in C4R. Phenotype data includes 113 variables for 7880 REGARDS participants in C4R. ]]>
REGARDS Inclusion Criteria: Aged 45 years or older African American or white REGARDS Exclusion Criteria: Race other than African American or whiteActive treatment for cancer Medical conditions that would prevent long-term participation Cognitive impairment, judged by the telephone interviewer Residence in or inclusion on a waiting list for a nursing home Inability to communicate in English REGARDS C4R Inclusion Criteria: REGARDS participants who: Are active Have completed the 2nd in-home exam ]]>
The (REGARDS) cohort is one of the nation's largest, most comprehensive population-based cohorts, and it uses innovative home- and telephone-based data collection. REGARDS centrally recruited and initially examined 30,239 Black and White men and women aged ≥45 years in 2003-7 to understand why Southerners and Black Americans have a higher incidence of stroke and related diseases that affect brain health. REGARDS has conducted annual follow-up with participants since enrollment and pursues medical records for relevant events. In 2020, REGARDS worked with C4R to understand the impact of SARS-CoV2 on the cohort.]]>