Heterogeneity and horizontal pleiotropy of instrumental variables.

NIAID Data Ecosystem2026-05-02 收录

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https://figshare.com/articles/dataset/Heterogeneity_and_horizontal_pleiotropy_of_instrumental_variables_/26258755 数据链接链接失效反馈

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资源简介：

Heterogeneity and horizontal pleiotropy of instrumental variables.

创建时间：

2024-07-11

Table_1_Causal Effects of Genetically Predicted Cardiovascular Risk Factors on Chronic Kidney Disease: A Two-Sample Mendelian Randomization Study.XLSX

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Observational studies have demonstrated that cardiovascular risk factors are associated with chronic kidney disease (CKD). However, these observational associations are potentially influenced by the r

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Table1_Association of oxidative stress, programmed cell death, GSTM1 gene polymorphisms, smoking and the risk of lung carcinogenesis: A two-step Mendelian randomization study.DOCX

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Aim: We aimed to examine the association of oxidative stress, programmed cell death, smoking, and the GSTM1 gene in the risk of lung carcinogenesis. The two-step Mendelian randomization will reveal ev

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Table_3_Cathepsins and Parkinson’s disease: insights from Mendelian randomization analyses.CSV

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BackgroundParkinson’s disease (PD), the second most prevalent neurodegenerative condition, has a multifaceted etiology. Cathepsin-cysteine proteases situated within lysosomes participate in a range of

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DataSheet_5_Diseases of the musculoskeletal system and connective tissue and risk of breast cancer: Mendelian randomization study in European and East Asian populations.docx

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ObjectiveAssociations between diseases of the musculoskeletal system and connective tissue (MSCTD) and breast cancer (BC) have not been elucidated completely. The purpose of this study was to investig

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DataSheet_1_Serum cystatin C and stroke risk: a national cohort and Mendelian randomization study.docx

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PurposeThe debate over the causal and longitudinal association between cystatin C and stroke in older adults persists. Our aim was to assess the link between cystatin C levels, both measured and genet

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Heterogeneity and horizontal pleiotropy of instrumental variables.

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