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A Non-Cross-Coupling Approach to Arene-Bridged Macrocycles: Synthesis, Structure, and Direct, Regioselective Functionalization of a Cycloparaphenylene Fragment

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NIAID Data Ecosystem2026-03-09 收录
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https://figshare.com/articles/dataset/A_Non_Cross_Coupling_Approach_to_Arene_Bridged_Macrocycles_Synthesis_Structure_and_Direct_Regioselective_Functionalization_of_a_Cycloparaphenylene_Fragment/2051088
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A new synthetic strategy that employs a relatively unstrained, 1,4-diketo-bridged macrocycle as a precursor to a strained, 1,4-arene-bridged (bent para-phenylene) macrocycle has been developed. The distorted p-terphenyl nucleus (CPP fragment) of the macrocycle has been characterized by X-ray crystallography, and a direct, regioselective bromination protocol of the macrocyclic system is reported.
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2015-12-17
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