Maternal 75 g oral glucose tolerance test levels as a predictive factor formaternal and neonatal outcomes in women with gestational diabetes mellitus:A Cross- Sectional Study

BACKGROUNDGestational diabetes which affects 3% to 6% of all pregnancies is an important issue which should be handled with specific treatment in addition to routine antenatal care to reduce the risks of maternal and perinatal morbidity.METHODSThis was a one-year retrospective analysis of pregnant women with GDM who gave birth in our hospital between December 2020 and November 2021. We have a total of 5152 obstetric admissions, 3681 high risk cases, and 197 women diagnosed with gestational diabetes mellitus based on the IADPSG guideline. Due to incomplete data, 23 cases were excluded, bringing the total number of cases for final analysis to 174. Demographics , as well as their OGTT results, GDM treatment, mode of delivery, and maternal and neonatal outcomes, were all documented.RESULTSFor the 174 subjects, we calculated crude odds ratios for adverse pregnancy outcomes associated with abnormalities of the 75g OGTT, those patients with abnormal 1st hr 75g OGTT were more likely to have antepartum complications with odds ratio (OR) of 2.40 (95 % confidence interval [CI] 1.17 to 4.94), and have preterm babies with OR 4.2 ( 95% CI, 1.04 to 16.9). When all 3 criteria are elevated, patients were more likely to have antepartum complication with OD 3.09, (95% CI, 1.16 to 8.19), low APGAR score with OR 6.87 (95% CI 1.43- 34), and have preterm babies with OR 5.64 (95% CI 1.48- 21.5). There were no statistical significance on the other adverse pregnancy outcomesCONCLUSIONSOur results indicate that the 1- h OGTT values is positively predictive with adverse antepartum pregnancy outcomes and preterm births and abnormalities on all 3 criteria were found to be positive predictors of unfavorable antepartum outcomes, low APGAR score, and preterm births.