The crystal structue of PDE10A complexed with 14
收藏Protein Data Bank Japan2023-11-29 更新2026-03-28 收录
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The crystal structue of PDE10A complexed with 14 Descriptor: 8-[(E)-2-[5-methyl-1-[3-[3-(4-methylpiperazin-1-yl)propoxy]phenyl]benzimidazol-2-yl]ethenyl]quinoline, MAGNESIUM ION, ZINC ION, ... Authors: Yang, Y, Zhang, S, Zhou, Q, Huang, Y.-Y, Guo, L, Luo, H.-B. Deposit date: 2020-03-22 Release date: 2021-01-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.40008632403 Å) Cite: Discovery of highly selective and orally available benzimidazole-based phosphodiesterase 10 inhibitors with improved solubility and pharmacokinetic properties for treatment of pulmonary arterial hypertension. Acta Pharm Sin B, 10, 2020
创建时间:
2020-03-22



