Plasma biochemical values (mean ± SD) of each of the parameters indicated in each group of animals (N = 36; 6 animals/group).

Control (12h light/12h darkness; L:D); exposure to permanent light (24h L); exposure to darkness (22h D) with light sessions between 4 and 6 p.m.; injected with Adriamycin (AD), 12 h/12 h L:D; AD+L; AD+D. P<0.05 minimum significance level. LDH: lactate dehydrogenase; CK: creatinine-quinase; AST: aspartate aminotransferase; ALT: alanine aminotransferase. ap<0,001 vs control; bp<0,01 vs control; cp<0,05 vs control; fp<0,05 L vs D. gp<0,001 AD+L or AD+D vs AD; hp<0,01 AD+L or AD+D vs AD; ip<0,05 AD+L or AD+D vs AD; kp<0,01 AD+L vs AD+D; lp<0,05 AD+L vs AD+D.