IL-22 is not required to control bacterial burden or gastric inflammation in the mouse model.

(A) Bacterial burden was measured in WT and IL-22-/- mice that were infected with PMSS1 for 1 month or 3 months. Colony forming units (CFU) per gram of stomach tissues was calculated and is presented in the graph. (B) Levels of acute and chronic inflammation were scored on stomach tissue (in the corpus and antrum) at 1 month and 3 months post infection with strain PMSS1. Total inflammation as presented is the sum of acute and chronic inflammation. Statistical analysis was performed using Mann-Whitney U which resulted in no significant differences between the groups, and error bars represented mean ± SEM. See methods for scoring system (scale is 0–12).