Systematic survey of the alteration of the intestinal flora in rats with functional dyspepsia and modulation by multicomponent drugs

Trillions of microbes constitute the intestinal flora, which, when disequilibrated, cause a human microecological imbalance. The intestinal flora modulate not only the peripheral but also the central nervous system (CNS). Disorders of the gut-brain interaction, including irritable bowel syndrome (IBS), FD, and abdominal migraine, are often related to disorders of the intestinal flora. It has been reported that development of IBS, a functional gastrointestinal disorder, is related to the consumption of particular foods, and it can be assumed that the gastrointestinal microbiota has its own specific way of influencing the pathological state.