Supplementary material: Systematic literature review and meta-analysis of cardiovascular risk factor management in selected Asian countries

These are peer-reviewed supplementary materials for the article 'Systematic literature review and meta-analysis of cardiovascular risk factor management in selected Asian countries' published in the Journal of Comparative Effectiveness Research.Table S1: Queries used for searching PubMed, EMBASE, and IMSEAR.Table S2: PICOS Criteria.Table S3: Definitions of hypertension, dyslipidemia, and diabetes mellitus by the authors of included studiesTable S4: Definitions of awareness, treatment, and control rate by the authors of included studiesTable S5: Risk assessment of the studies included in the SLRFigure S1: Funnel plot for awareness rateFigure S2: Funnel plot for treatment rateFigure S3: Funnel plot for control rate among those with the risk factor of interestFigure S4: Funnel plot for control rate among those being treatedPRISMA ChecklistAim: There is a need to understand the management status of hypertension, dyslipidemia/hypercholesterolemia, and diabetes mellitus in the Asia–Pacific region (APAC). Methods: We conducted a systematic literature review and meta-analysis to summarize the awareness, treatment, and/or control rates of these risk factors in adults across 11 APAC countries/regions. Results: We included 138 studies. Individuals with dyslipidemia had the lowest pooled rates compared with those with other risk factors. Levels of awareness with diabetes mellitus, hypertension, and hypercholesterolemia were comparable. Individuals with hypercholesterolemia had a statistically lower pooled treatment rate but a higher pooled control rate than those with hypertension. Conclusion: The management of hypertension, dyslipidemia,and diabetes mellitus was suboptimal in these 11 countries/regions.

本数据集为发表在《比较效果研究杂志》上的文章《特定亚洲国家心血管风险因素管理的系统文献综述和荟萃分析》的同行评审补充材料。表 S1：用于搜索 PubMed、EMBASE 和 IMSEAR 的查询。表 S2：PICOS 标准。表 S3：纳入研究作者对高血压、血脂异常和糖尿病的定义。表 S4：纳入研究作者对意识、治疗和控制率的定义。表 S5：纳入研究的风险评估。图 S1：意识率的漏斗图。图 S2：治疗率的漏斗图。图 S3：具有特定风险因素的受试者控制率的漏斗图。图 S4：正在接受治疗的受试者控制率的漏斗图。PRISMA 清单。目标：有必要了解亚太地区（APAC）高血压、血脂异常/高胆固醇血症和糖尿病的管理状况。方法：我们进行了一项系统文献综述和荟萃分析，以总结 11 个 APAC 国家/地区的成年人心血管风险因素（包括高血压、血脂异常和高胆固醇血症）的意识、治疗和/或控制率。结果：我们纳入了 138 项研究。与具有其他风险因素的个体相比，血脂异常的汇总率最低。糖尿病、高血压和高胆固醇血症的意识水平相当。与高血压患者相比，高胆固醇血症患者的汇总治疗率统计上较低，但汇总控制率较高。结论：在这 11 个国家/地区，高血压、血脂异常和糖尿病的管理状况不尽如人意。