Expression data in patients with familial (FCS) and multifactorial chylomicronemia (MCM)

FCS and MCM appear highly similar disorders. However, they importantly differ in term of risk and response to treatments. Some sets of genes might be up or down regulated in both disorders and could partly explain those differences. We used microarrays to explore gene expression patterns in FCS and MCM patients to identify potential targets that can be selected for protein quantification and functional studies. Our study was conducted in a sample of 19 genetically confirmed FCS and 28 MCM patients as well as 15 normolipemic controls. Subjects gave their informed consent and all data were de-identified.