Descriptive statistics for cases and controls used in the current study.

1Non-endemic control” refers to age-matched Thai individuals who have never resided in an area with O. viverrini transmission.2A control refers to an O. viverrini-infected individual who is age, sex, and nearest neighbor matched to a “case” but are negative for Advanced Periductal Fibrosis.3A case refers to O. viverrini infected individual who is positive for Advanced Periductal Fibrosis.4A case in this column refers to an individual with histologically proven O. viverrini associated cholangiocarcinoma (CCA) from the biological repository of the Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Thailand.